56553-60-7 Sodium Triacetoxyborohydride CAS NO.56553-60-7

Huateng pharmaceutical has 5000 square meters of building Changsha in high tech Development Zone, with Dr. master more than 100 R & D personnel; the main business includes Huateng pharmaceutical product sales, custom synthesis, production services and products testing and analysis services.

Huateng pharmaceutical attaches great importance to technology development, and constantly introduce high-level talents, advanced equipment and the instrument configuration, let the company have a full range of synthetic technology and research and development capabilities, through the research of continuous exploration, the core technology has more than 100 patents.

At present, there are 10 thousand kinds of own R & D and production, including organic tin compounds, boron / boric acid ester, large and small molecules of PEG derivatives, biological reagents, VD derivatives, amino acid derivatives, pharmaceutical intermediates and other compounds. Equipped with NMR, Agilent GC, HPLC, gas chromatography, infrared spectrum gel permeation chromatography, and other high-end detection equipment, to ensure customer orders are efficient, high-quality completion.

Huateng pharmaceutical has advanced research laboratory, pilot plant and production, with a variety of synthetic instrument, low temperature reactor, high pressure hydrogenation reactor reaction equipment; company to complete the mg kg, G, and tons of orders and production tasks.

Huateng innovation is the soul and life of our management innovation, technological innovation, management innovation, innovation oriented, realize the rapid development of the enterprise and value.

Sodium triacetoxyborohydride, also known as sodium triacetoxyhydroborate, commonly abbreviated STAB, is a chemical compound with the formula Na(CH3COO)3BH. Like other borohydrides, it is used as a reducing agent in organic synthesis. This colourless salt is prepared by protonolysis of sodium borohydride with acetic acid:
NaBH4 + 3 HO2CCH3 → NaBH(O2CCH3)3 + 3 H2
Owing to the steric and electronic effects of the acetoxy groups, sodium triacetoxyborohydride is a milder reducing agent than sodium borohydride or even sodium cyanoborohydride. Furthermore, NaBH(OAc)3 avoids the toxic side-products generated by sodium cyanoborohydride. Sodium triacetoxyborohydride is especially suitable for reductive aminations of aldehydes and ketones.
However, unlike sodium cyanoborohydride, the triacetoxyborohydride is water-sensitive, and water cannot be used as a solvent with this reagent, nor is it compatible with methanol. It reacts only slowly with ethanol and isopropanol and can be used with these.
NaBH(OAc)3 may also be used for reductive alkylation of secondary amines with aldehyde-bisulfite adducts.